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KMID : 1134820160450071017
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Journal of the Korean Society of Food Science and Nutrition
2016 Volume.45 No. 7 p.1017 ~ p.1025
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Changes in Platycoside Components and Antimicrobial Activities of Bronchus Disease-Inducing Bacteria of Fermented Platycodon grandiflorum Root by Lactic Acid Bacteria
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Lee Ka-Soon
Seong Bong-Jae
Kim Sun-Ick
Jee Moo-Geun
Park Saet-Byul
Park Myeong-Hee
Park Shin-Young
Kim Hyun-Ho
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Abstract
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This study was performed in order to investigate changes in platycosides, as well as antimicrobial activities of bronchus diseases-inducing bacteria (Corynebacterium diphtheriae, Klebsiella pneumoniae, Staphylococcus aureus, and Streptococcus pyogenes) of Platycodon grandiflorum root (PGR) fermented by lactic acid bacteria (Leuconostoc mesenteroides N12-4, Leuc. mesenteroides N58-5, Lactobacillus plantarum N76-10, L. plantarum N56-12, Lactobacillus brevis N70-9, and L. brevis E3-8). Growth of L. plantarum on PGR was most active during lactic acid fermentation using different strains. Total platycoside, platycoside E, platycodin A, polygalacin D2, polygalacin D, and diapioplatycoside E contents of PGR fermented for 96 h at 37°C by Leuc. mesenteroides and L. plantarum increased, whereas contents of platycodin D and platycodin D3 were reduced. The antimicrobial activity on PGR fermented by L. plantarum N56-12 exhibited strong microbial proliferation for all four kinds of bronchus disease-inducing bacteria and was higher than that of non-fermented PGR extract. MIC of fermented PGR extract by L. plantarum N56-12 on C. diphtheriae, K. pneumoniae, S. aureus, and S. pyogenes were 45, 10, 50, and 25 mg/mL, respectively. Thus, this result shows that the antimicrobial activities of bronchus disease-inducing bacteria and platycoside content of PGR by L. plantarum N56-12 were higher than that of non-fermented PGR extract.
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KEYWORD
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Platycodon grandiflorum root, fermentation, lactic acid bacteria, platycosides, antimicrobial activity
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